Beyond HIV microbicides: multipurpose prevention technology products

Beyond HIV microbicides: multipurpose prevention technology products.

Multipurpose prevention technologies (MPTs) that aim to simultaneously prevent unintended pregnancy, HIV-1 infection and other sexually transmitted infections are among the most innovative and complex products currently in development within women's sexual and reproductive health care. In this review article, MPTs are placed within the wider context of combination products, combination drug pro...

Microbicides in HIV prevention.

Microbicides for HIV prevention

Although the HIV incidence rate has slowed in some countries, HIV remains a serious health challenge, particularly in the developing world. The epidemic is increasingly feminised, with young women at high risk of acquiring the virus. There is thus a clear requirement for acceptable woman-initiated methods of HIV prevention. Foremost among these are vaginally-applied substances known as microbic...

Microbicides: topical prevention against HIV.

Microbicides represent a potential intervention strategy for preventing HIV transmission. Vaginal microbicides would meet the need for a discreet method that women could use to protect themselves against HIV. Although early-generation microbicides failed to demonstrate efficacy, newer candidates are based on more potent antiretroviral (ARV) products. Positive data from the CAPRISA 004 trial of ...

Microbicides for the Prevention of HIV Infection

Preventive interventions beyond behavior modification and physical barrier methods are needed to alter the natural course of the global HIV epidemic. Women need HIV-prevention tools that they can control to safeguard their health and that of their families and communities. This review focuses on one of the most promising prevention tools currently under development, namely microbicides. Microbi...